Comparison of the effectiveness of reproductive health education intervention through different channels for female college students / 中国学校卫生

Objective@#To understand the knowledge of reproductive health among female college students and the effectiveness of intervention measures, so as to provide a reference for conducting reproductive health education and health guidance for female college students.@*Methods@#From March to November 2022, 1 019 female college students of grade 1 to 3 from a university were selected by convenient sampling method,who were included in the conventional group( n =315), WeChat group( n =462) and outpatient and peer group( n =242). The Outpatient and peer group was provided with reproductive health education and health knowledge manuals and relevant guidance by receiving medical staff, the conventional group received routine health education and guidance from the school, and the WeChat group received online reproductive health education and guidance on the WeChat platform. Survey questionnaires were filled out before and after reproductive health related education and health guidance, and the results were compared and analyzed.@*Results@#After intervention, the awareness rates of women’s menstrual cycle , ovulation period, AIDS detection window period and suitable contraceptive methods in outpatient and peer groups and WeChat group were higher than those in conventional group ( χ 2=26.78, 31.70, 61.50 and 13.96 respectively). The awareness rates of women s physiological time easy to be pregnant and unreliable contraceptive methods in outpatient and peer groups were higher than those in conventional group ( χ 2= 9.10 , 10.68), and the awareness rates of unreliable contraceptive methods and main precautions during menstruation were higher than those in WeChat group ( χ 2=9.10, 8.02). The awareness rate of emergency contraception methods in WeChat group was higher than that in conventional group ( χ 2=7.94). All the differences were statistically significant ( P <0.05). After intervention, the knowledge scores of reproductive physiology (2.55±1.09, 2.42±1.08), contraception (2.62±1.20, 2.53±1.06), sexually transmitted disease (2.89±1.35, 2.76±1.24) and the total score of reproductive health knowledge (12.82±3.94, 12.12±3.06) among female college students of the outpatient and peer group and WeChat group were higher than those in the conventional group (2.10± 0.91 , 2.33±1.09, 2.55±1.18, 11.39±3.07). The knowledge score of accidental pregnancy and induced abortion (1.78±0.91) and the total score of reproductive health knowledge (12.82±3.94) among female college students of the outpatient and peer group were higher than those in the conventional group and WeChat group (1.57±0.87, 1.62±0.87; 11.39±3.07, 12.12±3.06). All the differences were statistically significant ( F =14.94, 5.27, 5.28, 13.02; 4.15, 13.02, P <0.05).@*Conclusion@#Female college students lack comprehensive understanding of reproductive health related knowledge. The reproductive health education and health care guidance to female college students should be developed through multiple channels, which would improve the reproductive health knowledge cognition of female college students and promote the formation of good health care behavior.

Analysis on influenza vaccination rate and safety of children aged 6 months to 5 years in Shunyi District of Beijing from 2016 to 2021 / 中国生物制品学杂志

@#ObjectiveTo understand the influenza vaccination rate and influencing factors of children aged 6 months to 5 years in Shunyi District,Beijing in June from 2016 to 2021,and analyze the surveillance status of suspected adverse events following immunization(AEFI)after vaccination.MethodsThe data of influenza vaccination and AEFI report of children,influenza vaccination status and follow-up observation of children with underlying diseases after the trial implementation of“Vaccination Recommendations”in Shunyi District of Beijing from 2016 to 2021 were collected to analyze the coverage rate and AEFI report.ResultsFrom 2016 to 2021,a total of 11 996 children aged 6 months to 5 years were vaccinated with influenza vaccine in Shunyi District of Beijing,and the vaccination rate increased year by year(χ2=11 921. 129,P < 0. 01；χ2=11 921. 129,P < 0. 01；χ2_(trend)= 8 881. 396,P < 0. 01);With age,the influenza vaccination rate showed a rising trend(χ2_(trend)= 8 881. 396,P < 0. 01);With age,the influenza vaccination rate showed a rising trend(χ2= 4 073. 395,P < 0. 01；χ2= 4 073. 395,P < 0. 01；χ2_(trend)= 3 495. 611,P < 0. 01);The vaccination rate of children in urban areas was higher than that in rural areas(χ2_(trend)= 3 495. 611,P < 0. 01);The vaccination rate of children in urban areas was higher than that in rural areas(χ2= 497. 153,P < 0. 01). 9 children with underlying diseases who met the “Proposal of Vaccination Experts” were followed up and no adverse reaction was observed after being vaccinated with influenza vaccine.Conclusion In Shunyi District of Beijing,the influenza vaccination rate for children aged 6 months to 5 years was relatively low,and no adverse reactions different from other vaccines have been detected. It was safe and reliable to vaccinate children suffering from basic diseases under the guidance of“Vaccination Recommendations”.

Public health emergencies in schools and economic loss in Luoyang from 2010 to 2019 / 中国学校卫生

Objective@#To analyze public health emergencies in schools and associated economic loss in Luoyang from 2010 to 2019, and to provide suggestions for developing evaluation mechanism for economic loss of public health emergencies in school settings.@*Methods@#Data of public health emergencies in schools during 2010-2019 in Luoyang was analyzed by descriptive epidemiological method; the integrity and logicality of the economic losses reports in emergencies were assessed; the overall economic losses of emergent events of public health in schools were evaluated.@*Results@#Among the 60 public health emergencies reported during 2010 to 2019 in Luoyang, 24 (40.00%) occurred in schools. Infectious diseases accounted for 91.67%(22). The peaks of public health emergencies were in May and December. Among the 24 public health emergencies, 50.00%(12) occurred in primary schools, with 386 (58.22%) cases. Nearly 75.00% (18/24) of public health emergencies in schools were reported, among them, reports with reasonable integrity accounted for 5.56% (1/18) and reports with logicality accounted for 38.89% (7/18). The highest integrity rate was found in disease prevention and control system (75.00%), while health supervision and law enforcement ranked the lowest (20.83%). According to the economic losses, the expense used for disease control and prevention was in front of the row(￥429 000), while the expense used for health supervision ranked at the bottom(￥20 800).@*Conclusion@#The reporting rate of economic losses of school public health emergencies in Luoyang is relatively high, but there is still a big gap in the integrality and logicality of the data. It is necessary to improve the standard of direct network reports of economic losses and to establish an effective evaluation mechanism for accurately responding to public health emergencies and evaluating economic losses.

Anatomical morphology of the root and root canal system of the second permanent molar in the Uygur people / 口腔疾病防治

Objective @#To study the anatomical characteristics of the root and root canal system of the mandibular second permanent molar in the Uygur people and provide a reference for clinical practice.@*Methods @#A total of 125 mandibular second permanent molars were extracted from Uygur patients in hospitals in the Xinjiang Uygur Autonomous Region. Three-dimensional reconstruction was performed after micro-CT scanning. The number of root canals, the root canal type (Weine classification and Fan′s C-shaped canal classification) and the occurrence of lateral accessory canals were observed.@*Results @#A sex difference was not detected in the root number or root form (χ2 = 1.277, P = 0.259). The incidence of 2-rooted molars was 70.4% (n = 88); type 2-1 canals were most common in the mesial root, with an incidence of 29.5%, followed by type 1-1 and 2-2 canals (each with an incidence of 26.1%), and the distal root mostly had a type 1-1 canal (96.6%). The incidence of single-rooted molars was 28.8%, and the frequency of C-shaped (n = 28) and non-C-shaped (n = 8) single-rooted molars was 22.4% and 6.4%, respectively. A three-rooted molar was detected in one case. The incidence of accessory canals was 65.2%.@*Conclusion @# Uygur mandibular second molars are mainly composed of two roots, and the incidence of a single root and root canal fusion is low (including C-shaped canals). Two-rooted molars frequently have two mesial canals and one distal canal.

Review on research of the phytochemistry and pharmacological activities of Celosia argentea

ABSTRACT Celosia argentea L., Amaranthaceae, is widely used as traditional medicine with a long history in China. It is a unique source of Semen Celosiae whose contributions include purging the hepatic pathogenic fire, improving eyesight, and treating other eye diseases. Over 79 compounds from this plant were isolated and identified, mainly including saponins, peptides, phenols, fatty acids, and amino acids, of which saponins have been considered as the characteristic and active constituents of Celosia argentea. Experimental evidences manifested that Celosia argentea, with its active compounds, possesses wide-reaching biological activities such as hepatoprotection, tumor treatment, anti-diarrhea, anti-diabetes, anti-oxidant, anti-hypertension, and for treatment of a number of eye diseases. The objective of the study was to provide an overview of the ethno-pharmacology, chemical constituents, pharmacology, and related clinical applications of Celosia argentea, and to reveal their therapeutic potentials, and secure an evidence base for further research works on Celosia argentea.

Effects of moxibustion on immune function in children with cerebral palsy / 中国针灸

<p><b>OBJECTIVE</b>To compare the effects between moxibustion at Guanyuan (CV 4), Shenshu (BL 23), Zusanli (ST 36) and western medication on immune function in children with cerebral palsy.</p><p><b>METHODS</b>A total of 230 children with cerebral palsy were randomly divided into an observation group and a control group, 115 cases in each one. Patients in the observation group were treated with warm moxibustion at Guanyuan (CV 4), Shenshu (BL 23) and Zusanli (ST 36). Patients in the control group were treated with oral administration of pidotimod 10 mL every time. The treatment was given once a day, and 30 days were considered as one session for total 90 days. The changes of T-lymphoctyte subgroups, serum immunoglobulin and development quotient were compared 30 days, 60 days and 90 days into treatment respectively; also the occurrence rate.of disease was observed during 6-month and 12-month follow-up visit.</p><p><b>RESULTS</b>The T-lymphoctyte subgroups (CD3+, CD4+, CD4+/CD8+), serum immunoglobulin (IgG, IgA) and development quotient were significantly improved 30 days, 60 days and 90 days into treatment (P < 0.01, P < 0.05). Regarding the changes of CD3+, CD4+, CD4+/CD4+, IgG, IgA and development quotient, the control group was superior to the observation group 30 days into treatment (all P < 0.05), and the control group was similar to the observation group 60 days into treatment (all P > 0.05), and the observation group was superior to the control group 90 days into treatment (all P < 0.05). There was no significant difference of CD8+ and IgM before and after treatment in two groups (all P > 0.05). The rate of adverse events was 7.0% (8/115) in the observation group, which was lower than 23.5% (27/115) in the control group (P < 0.01); during 6-month and 12-month follow-up visit, the occurrence rate of disease in the observation group was lower than that in the control group (P < 0.05).</p><p><b>CONCLUSION</b>Moxibustion at Guanyuan (CV 4), Shenshu (BL 23) and Zusanli (ST 36) can improve immune function of children with cerebral palsy, which is superior to pidotimod.</p>

Validity and Reproducibility of a Revised Semiquantitative Food Frequency Questionnaire (SQFFQ) for Women of Age-group 12-44 Years in Chengdu.

To find a credible nutritional screening tool for evaluating relationship between nutritional status and diseases in Chengdu female residents, the reliability and validity of a revised semi-quantitative food frequency questionnaire (SQFFQ) were tested. The validity was assessed by comparing the SQFFQ with the ‘standard’ method of 3 days’ dietary recall, and the reliability was assessed by comparing the first SQFFQ with the second SQFFQ at 4 weeks interval. Correlation analysis showed that, for reliability, the average correlation coefficient (CC) of 22 kinds of nutrients was 0.66 and reduced to 0.60 after adjusting for energy; the average of intra-class correlation coefficients (ICC) was 0.65. For validity, the average CC was 0.35 and remained stable after adjusting for CC of energy or nutrients. Validity of 17 nutrients in SQFFQ survey had correlation with result of 3 days’ dietary recall. The results showed that the revised SQFFQ can be used for investigating the role of nutrients in development of disease in Chengdu female residents.

Experimental Study of Antitoxic Effect of Sodium Selenite on Guinea Pig Cochlea Injury Induced by Gentamicin in Vivo / 中国康复理论与实践

@#ObjectiveTo explore the effect of sodium selenite on gentamicin-induced ototoxicity.MethodsTwenty guinea pigs were randomly divided into the experimental group and control group with 10 animals in each group. The animals were treated with i.m injection of gentamicin (200 mg/kg/d for 8 consecutive days, and at same time, the experimental group was added with p.o tablet of sodium selenite (1 mg/kg/d). Before and after the administration, hearing function was evaluated by examination for auditory brain stem responses (ABR). The cochlear outer haircells were observed by scanning electronic microscope (SEM) and transmission electronic microscope (TEM).ResultsABR threshold of the control group was about 30 dB above that of the experimental group (P<0.01). The latency of waveⅠof the control group was about 0.23 ms above that of the experimental group (P<0.01). Under SEM, the cilia of the majority outer hair cells of the control group lodged even disappeared, while that of the experimental remained regular. Under TEM, in outer hair cells of the control group, mitochondrial crests were obscure, out-membrane was damaged and local protruding, the number of secondary lysosomes was increased, myeloid bodies appeared, but in the experimental group, outer hair cells basically remained normal.ConclusionSodium selenite has antitoxic effect on guinea pig cochlea injury induced by gentamicin in vivo.